It goes without saying that the Spaniard and the Argentine have created one of football's most memorable bonds. When you look at the statistics behind their career together, it just further cements their status as football's elite stars.
Barcelona fans have had the pleasure of seeing the two maestros play together 512 times. Of those games, they've tasted victory on 357 occasions - an impressive 70% win average.
Draws make up another 19% (98 matches) whilst the 57 losses represent the remaining 11%. The two men played alongside each other for more than a decade and never lost their desire to win.
After playing together for more than 14 seasons in the famous blue and red of Barcelona, Iniesta and Messi have accumulated a truly astonishing win ratio whilst challenging for La Liga and Champions League glory.
Having played his last ever game at the Camp Nou on Sunday, Iniesta and Messi's lethal partnership has come to an end. Whilst we'll likely never see the two legends play together again, we can always admire their formidable record.