After a modest start to the season in La Liga for Atletico as well as for Real Madrid, the two clubs will battle it out at the Wanda Metropolitano on Saturday to try and earn the bragging right in the local derby.
The new stadium of Los Rojiblancos will experience the fierce emotion of the Madrid derby for first time, where the loser will fall even further behind Barcelona in the race for the La Liga title.
Both sides are currently eight points behind the league leaders and Zinedine Zidane's side will go all out to try and spoil the party at the Metropolitano.
In fact, there is one devastating fact which Real Madrid have in their favour. Los Blancos have never lost on their first visit to an Atletico Madrid stadium.
And that has happened on two previous occasions. In 1929, the old Metropolitano stadium saw Real run out 3-0 winners and in 1967, the two sides played out a goalless draw at the Vicente Calderon. What will happen on the third occasion?